Biological Information

Background Information:

Interleukin 6 (IL-6) is a pro-inflammatory cytokine protein and mediator of the immune response. Also acts as an anti-inflammatory myokine. Secreted by T cells, macrophages, osteoblasts, and smooth muscle cells for a variety of functions, including stimulating immune response for bacterial infection, burns, trauma, inducing fever, stimulating osteoclast formation, and inducing inflammation. Also inhibits TNF-alpha and IL-1 and activates IL-1ra and IL-10, leading to anti-inflammatory activity. Agonist of the IL-6 receptor, and implicated in multiple inflammatory diseases, including systemic juvenile rheumatoid arthritis and diabetes mellitus susceptibility. Provided as 20 μg of dry powder alongside reconstitution buffer.

Target Class:

Cytokine

Family:

Interleukin

Sub Family:

IL-6 Family

Target Species:

Human

Usage

Product Type:

Recombinant Proteins

Application:

Drug Discovery & Development

Storage Conditions:

Store at -20°C. Please avoid multiple freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Additional Information

Brand:

Eurofins DiscoverX®