PKC eta, active

Background Information:

Protein kinase C h (PKCh) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphosphate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters. GenBank NM_006255. Translation conflicts with NM_006255, V108L and G109R reported in dbEST BG719560 and BM549890, and L392Q reported in dbEST BI913495, BQ051772 and AU136862.

Target Class:

Kinase

Family:

PKC

Sub Family:

Protein Ser/Thr

Protein Name:

PKCeta

Protein Aliases:

PKC-L|nPKC-eta

Accession Number:

NM_006255.3

UniProt Number:

P24723

Gene Name:

PRKCH

Gene ID:

5583

Gene Aliases:

PKC-L|PKCL|PRKCL

Target Species:

Human