Biological Information
Background Information:
Protein serine/threonine kinase PIM2 is a member of a small family of highly homologous kinases, including PIM1, PIM2, and PIM3, and all members are expressed in the thymus. Pim plays a role in cell survival, proliferation, differentiation and tumorigenesis. Overexpression of each of these members can promote lymphomagenesis in mice. Inhibition of PIM2 may be useful in the treatment of chronic lymphocytic leukemia (B-CLL) and non-Hodgkin's lymphomas (NHL). GenBank U77735
Target Class:
Kinase
Family:
CAMK
Sub Family:
Protein Ser/Thr
Protein Name:
Pim2
Protein Aliases:
Pim-2h
Accession Number:
NM_006875.2
UniProt Number:
Q9P1W9
Gene Name:
PIM2
Gene ID:
11040
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology