NEK11, active

Background Information:

NEK11 is a protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.

Target Class:

Kinase

Family:

Other Protein Kinase

Sub Family:

Protein Ser/Thr

Protein Name:

NEK11

Protein Aliases:

Never in mitosis A-related kinase 11|NimA-related protein kinase 11

Accession Number:

NM_024800.3; NM_145910.2

UniProt Number:

Q8NG66

Gene Name:

NEK11

Gene ID:

79858

Gene Aliases:

FLJ23495

Target Species:

Human