MST3, active

Background Information:

MST3 (Mammalian sterile 20-like kinase 3) is a serine/threonine protein kinase that belongs to the sterile 20 (STE20) family of kinases. It is involved in a variety of cellular processes, including cell cycle progression, cell migration, and apoptosis. Research has suggested that MST3 plays a role in several diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. It has been shown to promote cancer cell proliferation and survival, and inhibition of MST3 has been suggested as a potential cancer therapy. Additionally, MST3 has been implicated in the regulation of neuronal survival and synaptic plasticity, making it a potential target for the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MST3

Protein Aliases:

STE20-like kinase 3|sterile 20-like kinase 3

Accession Number:

NM_001032296.2; NM_003576.3

UniProt Number:

Q9Y6E0

Gene Name:

STK24

Gene ID:

8428

Gene Aliases:

MST-3|MST3|MST3B|STK3|STE20

Target Species:

Human