MINK, active

Background Information:

MINK protein is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. GenBank NM_015716

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MINK

Protein Aliases:

misshapen/NIK-related kinase

Accession Number:

NM_001024937.2; NM_015716.3; NM_153827.3; NM_170663.3

UniProt Number:

Q8N4C8

Gene Name:

MINK1

Gene ID:

50488

Gene Aliases:

B55|MINK|ZC3|MAP4K6|YSK2

Target Species:

Human