MAP4K5, active

Background Information:

MAP4K5 is a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MAP4K5

Protein Aliases:

germinal center kinase-related

Accession Number:

NM_198794.4

UniProt Number:

Q9Y4K4

Gene Name:

MAP4K5

Gene ID:

11183

Gene Aliases:

KHS1|GCKR|KHS

Target Species:

Human