Biological Information

Background Information:

Janus kinase 2 (JAK2) is a non-receptor tyrosine kinase belonging to the Janus family. It is activated by a variety of cytokine and growth factor receptors, resulting in signaling cascades that facilitate the activation of various downstream target genes. JAK2 mediates gene transcription through its well-characterized downstream signaling molecules, the signal transducers and activators of transcription proteins (STAT). GenBank NM_004972

Target Class:

Kinase

Family:

TK

Sub Family:

Protein Tyrosine

Protein Name:

JAK2

Protein Aliases:

JAK-2

Accession Number:

NM_004972.2

UniProt Number:

O60674

Gene Name:

JAK2

Gene ID:

3717

Gene Aliases:

JTK10

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology