HIPK4, active

Background Information:

HIPK4 (Homeodomain Interacting Protein Kinase 4) is a serine/threonine protein kinase that belongs to the HIPK (Homeodomain Interacting Protein Kinase) family of kinases. It is involved in the regulation of a variety of cellular processes, including transcriptional regulation, cell proliferation, and apoptosis. Research has suggested that HIPK4 plays a role in several diseases, including cancer and developmental disorders. In cancer, HIPK4 has been shown to promote tumor cell survival and proliferation, and alterations in HIPK4 expression and activity have been observed in various types of cancer. Additionally, HIPK4 has been implicated in the regulation of neural development and has been linked to developmental disorders such as autism spectrum disorder. HIPK4 has also been suggested as a potential therapeutic target in cancer, and efforts to develop small-molecule inhibitors of the kinase are underway.

Target Class:

Kinase

Family:

CMGC

Sub Family:

Protein Ser/Thr

Protein Name:

HIPK4

Accession Number:

BC034501.2

UniProt Number:

Q8NE63

Gene Name:

HIPK4

Gene ID:

147746

Gene Aliases:

FLJ32818

Target Species:

Human