Biological Information

Background Information:

FER (TYK3) is a nuclear and cytoplasmic non-receptor tyrosine kinase and able to affect transcription in the nucleus. FER is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, implicated in the regulation of myeloid differentiation. Inhibition of FER may be of benefit for the treatment of myeloid and prostate cancer as well as angiogenesis. GenBank NM_005246

Target Class:

Kinase

Family:

TK

Sub Family:

Protein Tyrosine

Protein Name:

Fer

Protein Aliases:

phosphoprotein NCP94|protein phosphatase 1, regulatory subunit 74

Accession Number:

NM_005246.2

UniProt Number:

P16591

Gene Name:

FER

Gene ID:

2241

Gene Aliases:

TYK3|PPP1R74

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology