EphA1, active

Background Information:

Eph family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Recently, the Eph-ephrin system has been found to be involved in vascular development, angiogenesis, tumor growth and metastasis as well as regulation of smooth muscle contractility, onset of platelet aggregation and to promote onset, growth and stability of the hemostatic plugs. GenBank AH007960

Target Class:

Kinase

Family:

RTK

Sub Family:

Protein Tyrosine

Protein Name:

EphA1

Protein Aliases:

EPH tyrosine kinase|EPH tyrosine kinase 1|Erythropoietin-producing hepatoma receptor|Tyrosine-protein kinase receptor EPH

Accession Number:

NM_005232.3

UniProt Number:

P21709

Gene Name:

EPHA1

Gene ID:

2041

Gene Aliases:

EPH

Target Species:

Human