Biological Information
Background Information:
Mammalian casein kinase 2α1 (CK2a1) is a highly conserved serine-threonine protein kinase that is constitutively expressed in all eukaryotic cell types including yeast, insects, and vertebrates. The enzyme can utilize GTP or ATP as a phosphate donor. Casein kinase activity is stimulated by mitogens in a cell type-specific manner during development and embryogenesis. Inhibition of CK2α1 may be useful in the treatment of human squamous cell carcinoma, adenocarcinoma of the lung, prostatic hyperplasia and lymphomas. GenBank J02853.1
Target Class:
Kinase
Family:
Other Protein Kinase
Sub Family:
Protein Ser/Thr
Protein Name:
CK2alpha1
Accession Number:
J02853
UniProt Number:
P68400
Gene Name:
CSNK2A1
Gene ID:
1457
Gene Aliases:
CK2A1
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -20°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology