Biological Information
Background Information:
Mammalian casein kinase 1 (CK1) gene family consists of seven different genes in mammals, CKIa, b, g1, g2, g3, d and e. These enzymes are important component of signal transduction pathways, regulates cell growth, division and differentiation, and the activities of a variety of oncoproteins and transcription factors. CSNK1G1 (Casein kinase I gamma1 isoform) plays an important role in cell survival and protects regulatory proteins from caspase-mediated degradation in apoptosis. Inhibitors may find clinical use for the treatment of Alzheimer's disease and amyotrophic lateral sclerosis. GenBank NM_022048
Target Class:
Kinase
Family:
CK1
Sub Family:
Protein Ser/Thr
Protein Name:
CK1gamma1
Accession Number:
NM_022048.3
UniProt Number:
Q9HCP0
Gene Name:
CSNK1G1
Gene ID:
53944
Gene Aliases:
CK1gamma1
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology