Casein Kinase 1delta (aa 1-294), active

Background Information:

Mammalian casein kinase 1 (CK1, ) gene family consists of seven different genes in mammals, CKIa, b, g1, g2, g3, d and e. These enzymes are important components of signal transduction pathways and regulate cell growth, division and differentiation, and the activities of a variety of oncoproteins and transcription factors. CSNK1D (Casein kinase I delta isoform, CKI-delta, CKId) plays an important role in cell survival and protects regulatory proteins from caspase-mediated degradation in apoptosis. Inhibitors may find clinical use for the treatment of Alzheimer's disease and amyotrophic lateral sclerosis. GenBank AB063114. This is a rat cDNA that is 100% identical to human casein kinase 1 delta over 1-294 of the predicted amino acid sequence.

Target Class:

Kinase

Family:

CK1

Sub Family:

Protein Ser/Thr

Protein Name:

CK1delta

Protein Aliases:

CKId|Tau-protein kinase CSNK1D

Accession Number:

NM_001893.3; NM_139062.1

UniProt Number:

P48730

Gene Name:

CSNK1D

Gene ID:

1453

Gene Aliases:

HCKID|CKID|CKIdelta

Target Species:

Human