CSK, active

Background Information:

CSK (C-SRC, c-Src tyrosine kinase) is a non-receptor tyrosine kinase that catalyzes the tyrosine phosphorylation of Src family members at C-terminal, promoting an intramolecular association between the phosphotryosine and the Src homology 2 (SH2) domain and negatively regulating Src catalytic activity in vivo. Although CSK has substantial homology to Src kinases, it lacks the C-terminal regulatory tyrosine found in Src kinases. GenBank X60114 (CDS GB 30314)

Target Class:

Kinase

Family:

TK

Sub Family:

Protein Tyrosine

Protein Name:

CSK

Protein Aliases:

C-Src kinase|Protein-tyrosine kinase CYL

Accession Number:

X60114.1

UniProt Number:

P41240

Gene Name:

CSK

Gene ID:

1445

Target Species:

Human