CRIK, active

Background Information:

CRIK, also known as Citron Rho-Interacting Serine/Threonine Kinase, is a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Target Class:

Kinase

Family:

AGC

Sub Family:

Protein Ser/Thr

Protein Name:

CRIK

Protein Aliases:

serine/threonine kinase 21

Accession Number:

NM_007174.2

UniProt Number:

O14578

Gene Name:

CIT

Gene ID:

11113

Gene Aliases:

KIAA0949|STK21|CRIK

Target Species:

Human