AMPK (alpha1, beta1, gamma1), active

Background Information:

AMPK (α1, β1, γ1) protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. GenBank AF100763 / GenBank NM_006253 / GenBank NM_002733

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

AMPKalpha1

Protein Aliases:

AMPK, alpha, 1

Accession Number:

AF100763; NM_006253; NM_002733

UniProt Number:

Q13131

Gene Name:

PRKAA1

Gene ID:

5562

Gene Aliases:

AMPKa1

Target Species:

Human