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Kinase - PathHunter® Cell-Based Kinase Assays

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Kinases

– Whole-cell Assay Platform for Screening Cytosolic Tyrosine Kinase Activity

PathHunter® eXpress Cytosolic Tyrosine Kinase Assays

PathHunter® eXpress cytosolic tyrosine kinase assay kits are cell-based, functional complete out-of-the box solutions that offer convenience. The kits include pre-validated engineered cells and reagents to ensure robust and reliable performance every time you run the kit. By eliminating lengthy, time-consuming and expensive cell culture, PathHunter eXpress kits enable you to identify functional antibodies or small molecule inhibitors against specific cytokine receptors and cytosolic tyrosine kinases.

Product Features

 No tissue-culture required
 Target-specific functional assay
 Optimized protocol that eliminates assay development
 Assay-ready frozen cells in a 96-well format
 Read on any standard benchtop luminometer

How does it work?

PathHunter® eXpress cytoplasmic tyrosine kinase Assay kits come with pre-validated ready-to-assay cells, detection reagents, cell plating media and plates. Simply thaw and plate the cells, and run the assay with your compounds. Assay-ready frozen cells are based on DiscoverRx's PathHunter® technology, Read More»

Kit Contents

 Assay-ready, frozen PathHunter® eXpress cells
 Optimized Cell Plating Medium
 PathHunter® Detection Reagents
 96-well Tissue Culture Treated Plates
 V-bottom compound dilution plate

For instrument compatibility, please click here.


 
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Available Literature

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Targets
Catalog #
Cell Line
Details
Price
CSF3R-JAK1
93-0809E3CPO
U2OS
GHR-JAK1
93-0756E3CPO
U2OS
GHR-JAK2
93-0829E3CPO
U2OS
PRLR-JAK1
93-0686E3CPO
U2OS
PRLR-JAK2
93-0687E3CPO
U2OS

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