Biological Information | |
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Background Information: | NEK (NIMA-Related Kinase) Ser/Thr kinase family includes at least 11 members and is involved in regulation of mitosis. Overexpression of active NEK2 (NLK1) induces a striking splitting of centrosomes, whereas prolonged expression of either active or inactive NEK2 leads to dispersal of centrosomal material and loss of a focused microtubule-nucleating activity.
GenBank NM_002497 |
Target Class: | Kinase |
Accession Number: | NM_002497.2 |
Target Name: | NEK2 |
Target Aliases: | NEK2, NLK1, NLK, NEK2A, HsPK21 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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