Brk, active

N-terminal 6His-tagged recombinant, human full length BRK.

Catalog #: 14-613

$399.00$2,989.00


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Biological Information
Background Information:
BRK (breast tumor kinase, PTK6) is a non-receptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. BRK overexpression is frequently observed in breast cancer and several other cancer types. Studies reveal BRK translocates to membrane ruffles, where it colocalizes with paxillin during cell migration. Inhibition of BRK may be useful for the treatment of breast and other cancers. GenBank NM_005975
Target Class:
Kinase
Accession Number:
NM_005975.2
Target Name:
BRK
Target Aliases:
PTK6, FLJ42088, BRK
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-613x Datasheet

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