Biological Information | |
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Background Information: | AXL is a member of AXL protein-tyrosine kinase family and expressed human myeloid leukemia cells. Gas6, the protein product of the growth arrest-specific gene 6 (gas6), a member of the vitamin K-dependent protein family, was identified as a ligand for the Axl/Sky family of receptor tyrosine kinases. Gas6/Axl signaling has been related to the cell growth and protection from apoptosis in normal and cancer cells.
GenBank NM_021913. The recombinant protein also contains the conflict Q764R with respect to GenBank NM_021913. This substitution is reported in GenBank BC032229. The residue coordinates in the native sequence are given. |
Target Class: | Kinase |
Family: | Receptor Tyrosine Kinase (RTK): Type XI RTK: TAM Receptor Family |
Accession Number: | NM_001699.3; NM_021913.2 |
Target Name: | Axl |
Target Aliases: | AXL receptor tyrosine kinase |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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