Biological Information | |
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Background Information: | Apoptosis signal-regulating kinase 1 (ASK1) is a serine/threonine protein kinase and identified as a MAPKKK which activates the c-Jun N-terminal kinase (JNK) and p38 MAP kinase pathways and is required for TNFalpha;-induced apoptosis. ASK1 suggests possible mechanisms for redox regulation of the apoptosis signal transduction pathway as well as the effects of antioxidants against cytokine- and stress-induced apoptosis.
GenBank NM_005923 |
Target Class: | Kinase |
Accession Number: | NM_005923.3 |
Target Name: | Ask1 |
Target Aliases: | MAP3K5, MEKK5, ASK1, ASK-1, MAPKKK5 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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