PAK3, active

C-terminal 6His-tagged recombinant, human full length PAK3.

Catalog #: 14-683

$399.00$2,989.00


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Biological Information
Background Information:
PAK3 (P21 (RAC1) Activated Kinase 3) is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. PAK3 plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. PAK3 also plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity, and acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. GenBank AB102659
Target Class:
Kinase
Accession Number:
NM_002578.2
Target Name:
PAK3
Target Aliases:
PAK3, oligophrenin-3, CDKN1A, OPHN3, PAK3beta, PAK-3, Beta-PAK, OTTHUMP00000062894, Oligophrenin-3, hPAK3, MRX47, MRX30, bPAK
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-683x Datasheet

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