Biological Information | |
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Background Information: | MST1 and MST2 contain a putative caspase cleavage site at the junction of the catalytic domain and the C-terminal region. MST is involved in a positive feedback loop in possible association with the SAPK and p38-MAPK pathways. MST1 has been shown activated in cellular apoptosis induced by a variety of stimuli. Inhibition of MST1 may inhibit Raf-1-mediated cell proliferation and result in apoptosis.
GenBank NM_006282 |
Target Class: | Kinase |
Accession Number: | NM_006282.2 |
Target Name: | MST1 |
Target Aliases: | STK4, DKFZp686A2068, MST-1, MST1, KRS2, YSK3 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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